TIAM1 anticorps

N° du produit ABIN5541409

Cet anticorps anti-TIAM1 Monoclonal Souris (Clone F5S F6-2) (ABIN5541409) détecte spécifiquement TIAM1 dans WB et IHC (fro). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour TIAM1 anticorps (ABIN5541409)

Antigène: TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TIAM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: F5S F6-2

Détail du produit anti-TIAM1 anticorps

Specificité: This antibody clone F5S F6.2 is directed against the N-terminal region of Tiam1.

Purification: Purified

Immunogène: T-cell lymphoma invasion and metastasis-inducing protein 1 (Tiam1).

Isotype: IgG2b

Information d'application

Indications d'application: Western Blot. Immunohistochemistry on Frozen Sections.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Buffer System: PBS Preservatives: 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur TIAM1

Antigène: TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

Autre désignation: tiam1

Sujet: Tiam1, also known as T-cell lymphoma invasion and metastasis-inducing protein 1, is a protein that in humans is encoded by the TIAM1 gene. TIAM1 is tightly associate with BAIAP2 as a subunit. It contains one DH (DBL-homology) domain, one PDZ domain, two PH domains and one Ras-binding RBD domain. TIAM1 modulates the activity of Rho GTP-binding proteins and connects extracellular signals to cytoskeletal activities. In addition, TIAM1 activates Rac1, CDC42, and to a lesser extent RhoA. TIAM1 is found in virtually all tumor cell lines examined including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.

UniProt: Q13009