14-3-3 sigma/SFN anticorps (C-Term)

N° du produit ABIN5541548

Cet anticorps Lapin Polyclonal détecte spécifiquement 14-3-3 sigma/SFN dans WB, IF, ICC, IHC (p) et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour 14-3-3 sigma/SFN anticorps (C-Term) (ABIN5541548)

Antigène: 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp 14-3-3 sigma/SFN est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-14-3-3 sigma/SFN anticorps

Épitope: C-Term

Specificité: This antibody recognizes Human SFN (C-term). Other species not tested.

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 222-248 amino acids from the C-terminal region of Human SFN.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western blotting: 1/1000. Immunohistochemistry on Paraffin Sections: 1/10-1/50. Flow Cytometry: Immunofluorescence:

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS Preservatives: 0.09 % (W/V) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur 14-3-3 sigma/SFN

Antigène: 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

Autre désignation: 14-3-3 protein sigma,sfn

Sujet: Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axolly transported to the nerve termils. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of sigl transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in sigling pathways mediated by serine/threonine protein kises. Evidence indicates 14-3-3 is required for Raf 1 kise activity and phosphorylation among many other functions.

UniProt: P31947

Pathways: Signalisation p53, Myometrial Relaxation and Contraction