P-Selectin anticorps (Biotin)

N° du produit ABIN5541729

L’anticorps Souris Monoclonal anti-P-Selectin a été validé pour FACS. Il convient pour détecter P-Selectin dans des échantillons de Humain et Primate.

Aperçu rapide pour P-Selectin anticorps (Biotin) (ABIN5541729)

Antigène: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Reactivité: Humain, Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp P-Selectin est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Clone: AK4

Détail du produit anti-P-Selectin anticorps (Biotin)

Specificité: This antibody recognizes CD62P (P-selectin), a 140 kD single chain type I transmembrane glycoprotein present in secretory alpha-granules in platelets, in Weibel-Palade bodies in endothelial cells and in megakaryocytes it is relocated to the plasma membrane upon activation.

Immunogène: Human platelets

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur P-Selectin

Antigène: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Autre désignation: cd62p,p-selectin

Sujet: CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster.

UniProt: P16109