CD4 anticorps

N° du produit ABIN5541941

Cet anticorps Souris Monoclonal détecte spécifiquement CD4 dans FACS, IP et IHC (fro). Il présente une réactivité avec des échantillons de Cheval. Il a été cité dans 2+ publications.

Aperçu rapide pour CD4 anticorps (ABIN5541941)

Antigène: CD4

Reactivité: Cheval

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD4 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: CVS4

Détail du produit anti-CD4 anticorps

Specificité: This anitbody reacts with T-helper cells, it recognises a 58 kDa cell surface glycoprotein that is primarily expressed on a subpopulation of equine T lymphocytes and considered to be the equine homologue of human CD4. Species: Equine (Horse).

Purification: Affinity chromatography on Protein G from tissue culture supernatant

Immunogène: Equine thymocytes

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry : 1/25-1/200, use 10 μL of this working dilution to label 10e6 cells in 100 μL. Immunohistochemistry on Frozen sections. Immunoprecipitation.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Containing 0.09 % Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Références pour anticorps anti-CD4 (ABIN5541941)

Go, Zhang, Timoney, Cook, Horohov, Balasuriya: "Complex interactions between the major and minor envelope proteins of equine arteritis virus determine its tropism for equine CD3+ T lymphocytes and CD14+ monocytes." dans: Journal of virology, Vol. 84, Issue 10, pp. 4898-911, (2010) (PubMed).

Goodman, Loregian, Perkins, Nugent, Buckles, Mercorelli, Kydd, Palù, Smith, Osterrieder, Davis-Poynter: "A point mutation in a herpesvirus polymerase determines neuropathogenicity." dans: PLoS pathogens, Vol. 3, Issue 11, pp. e160, (2008) (PubMed).

Détails sur CD4

Antigène: CD4

Autre désignation: cd4

Sujet: CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes (helper/inducer T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.

UniProt: F6Y6X8

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events