MFAP4 anticorps (AA 22-255)

N° du produit ABIN5542149

L’anticorps Souris Monoclonal anti-MFAP4 a été validé pour WB et EIA. Il convient pour détecter MFAP4 dans des échantillons de Humain.

Aperçu rapide pour MFAP4 anticorps (AA 22-255) (ABIN5542149)

Antigène: MFAP4 (Microfibrillar-Associated Protein 4 (MFAP4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MFAP4 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT12D11

Détail du produit anti-MFAP4 anticorps

Épitope: AA 22-255

Purification: Protein-A affinity chromatography

Immunogène: Recombinant human MFAP4 (22-255aa) purified from E. coli

Isotype: IgG1

Information d'application

Indications d'application: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur MFAP4

Antigène: MFAP4 (Microfibrillar-Associated Protein 4 (MFAP4))

Autre désignation: mfap4

Sujet: Several microfibril associated proteins (MFAPs) have been cloned, including MFAP1, MFAP3 and MFAP4. The MFAP1 and MFAP3 genes are localized near the fibrillin genes FBN1 and FBN2, respectively. Mutations in FBN1 are linked to Marfan syndrome. Mutations in FBN2 have been linked to congenital contractural arachnodactyly. This suggests roles for MFAP1 and MFAP3 in heritable diseases affecting microfibrils. Deletion of MFAP4 was found in 30 of 31 patients with Smith-Magenis syndrome (SMS), a clinically recognizable multiple congenital anomaly/mental retardation syndrome. Also, MFAP4 play an important role in calcium-dependent cell adhesion or intercellular interactions. These structural features of MFAP4 suggest that it is an extracellular matrix protein involved in cell adhesion or intercellular interactions.

UniProt: P55083