LDLR anticorps (AA 22-150)

N° du produit ABIN5542334

Cet anticorps Souris Monoclonal détecte spécifiquement LDLR dans IHC, ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour LDLR anticorps (AA 22-150) (ABIN5542334)

Antigène: LDLR (Low Density Lipoprotein Receptor (LDLR))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LDLR est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 1B10H10

Détail du produit anti-LDLR anticorps

Épitope: AA 22-150

Fonction: LDLR Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human LDLR (AA: 22-150) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur LDLR

Antigène: LDLR (Low Density Lipoprotein Receptor (LDLR))

Autre désignation: LDLR

Sujet: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.r

Poids moléculaire: 95.4 kDa

ID gène: 3949

UniProt: P01130

Pathways: Hepatitis C, Lipid Metabolism