RAB8A anticorps (AA 68-207)

N° du produit ABIN5542342

Cet anticorps anti-RAB8A est un anticorps Souris Monoclonal détectant RAB8A dans ELISA et FACS. Adapté pour Humain.

Aperçu rapide pour RAB8A anticorps (AA 68-207) (ABIN5542342)

Antigène: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RAB8A est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 7G8B11

Détail du produit anti-RAB8A anticorps

Épitope: AA 68-207

Fonction: Rab8 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human Rab8 (AA: 68-207) expressed in E. Coli.

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur RAB8A

Antigène: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Autre désignation: Rab8

Sujet: The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97 % , 96 %, and 51 % similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.

Poids moléculaire: 23.7 kDa

ID gène: 4218

UniProt: P61006

Pathways: M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome