TARDBP anticorps (AA 126-260)
Aperçu rapide pour TARDBP anticorps (AA 126-260) (ABIN5542391)
Antigène
Voir toutes TARDBP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 126-260
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Fonction
- TARDBP Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human TARDBP (AA: 126-260) expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- TARDBP (TAR DNA Binding Protein (TARDBP))
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Autre désignation
- TARDBP
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Sujet
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HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
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Poids moléculaire
- 44.7 kDa
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ID gène
- 23435
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UniProt
- Q13148
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Pathways
- Positive Regulation of Peptide Hormone Secretion
Antigène
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