IRAK3 anticorps (AA 454-596)
Aperçu rapide pour IRAK3 anticorps (AA 454-596) (ABIN5542522)
Antigène
Voir toutes IRAK3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 454-596
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Fonction
- IRAK3 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human IRAK3 (AA: 454-596) expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
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Autre désignation
- IRAK3
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Sujet
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This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
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Poids moléculaire
- 67.8 kDa
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ID gène
- 11213
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UniProt
- Q9Y616
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Pathways
- Signalisation TLR, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
Antigène
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