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MAP2K3 anticorps (AA 1-138)

MAP2K3 Reactivité: Humain WB, IHC, ELISA, ICC, FACS Hôte: Souris Monoclonal 2E12D11 unconjugated
N° du produit ABIN5542528
  • Antigène Voir toutes MAP2K3 Anticorps
    MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
    Épitope
    • 25
    • 19
    • 15
    • 15
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-138
    Reactivité
    • 139
    • 101
    • 81
    • 11
    • 10
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 143
    • 11
    Souris
    Clonalité
    • 130
    • 24
    Monoclonal
    Conjugué
    • 70
    • 9
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    Cet anticorp MAP2K3 est non-conjugé
    Application
    • 120
    • 48
    • 40
    • 39
    • 32
    • 28
    • 21
    • 9
    • 8
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human MAP2K3 (AA: 1-138) expressed in E. coli.
    Clone
    2E12D11
    Isotype
    IgG1
    Top Product
    Discover our top product MAP2K3 Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Antigène
    MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
    Autre désignation
    MAP2K3 (MAP2K3 Produits)
    Synonymes
    anticorps MAPKK3, anticorps MEK3, anticorps MKK3, anticorps PRKMK3, anticorps SAPKK-2, anticorps SAPKK2, anticorps AW212142, anticorps Prkmk3, anticorps mMKK3b, anticorps Mkk3, anticorps mitogen-activated protein kinase kinase 3, anticorps mitogen activated protein kinase kinase 3, anticorps MAP kinase activator XMEK3, anticorps MAP2K3, anticorps Map2k3, anticorps map2k3
    Sujet

    Description: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene.,

    Aliases: MEK3, MKK3, MAPKK3, PRKMK3, SAPKK2, SAPKK-2

    Poids moléculaire
    39.3 kDa
    ID gène
    5606
    HGNC
    5606
    Pathways
    Signalisation MAPK, Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2
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