TCL1A anticorps (AA 10-104)

N° du produit ABIN5542543

Cet anticorps anti-TCL1A est un anticorps Souris Monoclonal détectant TCL1A dans ELISA et FACS. Adapté pour Humain.

Aperçu rapide pour TCL1A anticorps (AA 10-104) (ABIN5542543)

Antigène: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TCL1A est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 2E3A5

Détail du produit anti-TCL1A anticorps

Épitope: AA 10-104

Fonction: TCL1A Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human TCL1A (AA: 10-104) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur TCL1A

Antigène: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Autre désignation: TCL1A

Sujet: Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).

Poids moléculaire: 13.5 kDa

ID gène: 8115

UniProt: P56279

Pathways: Stem Cell Maintenance