PMS2 anticorps (AA 748-851)

N° du produit ABIN5542596

L’anticorps anti-PMS2 Monoclonal produit chez le Souris a été validé pour ELISA, FACS et ICC. Il convient pour la détection de PMS2 dans des échantillons provenant de Humain. }

Aperçu rapide pour PMS2 anticorps (AA 748-851) (ABIN5542596)

Antigène: PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PMS2 est non-conjugé

Application: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 1E9D11

Détail du produit anti-PMS2 anticorps

Épitope: AA 748-851

Fonction: PMS2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human PMS2 (AA: 748-851) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur PMS2

Antigène: PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))

Autre désignation: PMS2

Sujet: This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.

Poids moléculaire: 95.8 kDa

ID gène: 5395

UniProt: P54278

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response