Caspase 3 anticorps (AA 29-175)

N° du produit ABIN5542609

Cet anticorps anti-Caspase 3 est un anticorps Souris Monoclonal détectant Caspase 3 dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Caspase 3 anticorps (AA 29-175) (ABIN5542609)

Antigène: Caspase 3 (CASP3)

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Caspase 3 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 3D4D10

Détail du produit anti-Caspase 3 anticorps

Épitope: AA 29-175

Fonction: CASP3 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CASP3 (AA: 29-175) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur Caspase 3

Antigène: Caspase 3 (CASP3)

Autre désignation: CASP3

Sujet: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

Poids moléculaire: 31.6 kDa

ID gène: 836

UniProt: P42574

Pathways: Apoptose, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation