Caspase 3 anticorps (AA 29-175)

N° du produit ABIN5542609

Détail du produit anti-Caspase 3 anticorps

Antigène: Caspase 3 (CASP3)

Épitope: AA 29-175

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Caspase 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purification: purified

Immunogène: Purified recombinant fragment of human CASP3 (AA: 29-175) expressed in E. coli.

Clone: 3D4D10

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: , FCM:

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur Caspase 3

Antigène: Caspase 3 (CASP3)

Autre désignation: CASP3 (CASP3 Produits)

Synonymes: anticorps CPP32, anticorps CPP32B, anticorps SCA-1, anticorps A830040C14Rik, anticorps AC-3, anticorps Apopain, anticorps CC3, anticorps Caspase-3, anticorps Lice, anticorps Yama, anticorps mldy, anticorps xcpp32, anticorps casp3, anticorps zgc:100890, anticorps CASP-3, anticorps caspase-3, anticorps caspase 3, anticorps caspase 3 S homeolog, anticorps caspase 3, apoptosis-related cysteine peptidase a, anticorps caspase 3, apoptosis-related cysteine peptidase, anticorps CASP3, anticorps Casp3, anticorps casp3.S, anticorps casp3a

Sujet:

Description: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

Aliases: CPP32, SCA-1, CPP32B

Poids moléculaire: 31.6 kDa

ID gène: 836

HGNC: 836

Pathways: Apoptose, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation