IRF7 anticorps

N° du produit ABIN5557323

Cet anticorps Lapin Monoclonal détecte spécifiquement IRF7 dans WB et IF (cc). Il présente une réactivité envers Humain.

Aperçu rapide pour IRF7 anticorps (ABIN5557323)

Antigène: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp IRF7 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 2A1

Détail du produit anti-IRF7 anticorps

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: Recombinant human IRF7 protein, around 200-300aa.

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur IRF7

Antigène: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Autre désignation: IRF7

Sujet:

Synonyms: signal transducers and activators of transduction 4, CIS4, HSPC060, SOCS4, SOCS6, SSI4, STAI4, STAT 4, STAT4, STATI4, Suppressor of cytokine signaling 6, STAT4_HUMAN.

Background: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011].

ID gène: 3665

UniProt: Q92985

Pathways: Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy