Recombinant EIF4E anticorps (pSer209)
Aperçu rapide pour Recombinant EIF4E anticorps (pSer209) (ABIN5557447)
Antigène
Voir toutes EIF4E AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer209
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Fonction
- phospho-eIF4E (Ser209) Recombinant Antibody
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Réactivité croisée
- Humain, Souris, Rat
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated Synthesised phosphopeptide derived from human EIF4E around the phosphorylation site of Ser209: SG(p-S)TT
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Isotype
- IgG
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Indications d'application
- WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(1:50-200), ICC/IF(1:50-100)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
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Autre désignation
- eIF4E
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Sujet
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Synonyms: CBP, EIF4F, AUTS19, EIF4E1, EIF4EL1, Eukaryotic translation initiation factor 4E, eIF-4E, eIF4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein
Background: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
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ID gène
- 1977
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UniProt
- P06730
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Pathways
- BCR Signaling
Antigène
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