Recombinant H2AFX anticorps (pSer139)

N° du produit ABIN5557485

Cet anticorps Lapin Monoclonal détecte spécifiquement H2AFX dans WB, IF, IHC (p) et IHC (fro). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant H2AFX anticorps (pSer139) (ABIN5557485)

Antigène: H2AFX (H2A Histone Family, Member X (H2AFX))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp H2AFX est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-H2AFX anticorps

Épitope: pSer139

Fonction: Phospho-H2AX (Ser139) Recombinant Antibody

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated Synthesized phosphopeptide derived from human Histone H2A.X around the phosphorylation site of Ser139:QA(p-S)QE.

Isotype: IgG

Information d'application

Indications d'application: WB(1:500-2000), IHC-P(1:200-1000), IHC-F(1:200-1000), IF(1:200-1000)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur H2AFX

Antigène: H2AFX (H2A Histone Family, Member X (H2AFX))

Autre désignation: Histone H2A.X

Sujet:

Synonyms: H2A histone family member X, Histone H2A.x, H2afx, H2a.x, H2ax, Hist5-2ax, H2A.X, H2A/X, H2AX, H2AFX, H2AX_HUMAN.

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Jul 2008].

ID gène: 3014

UniProt: P16104

Pathways: Telomere Maintenance, Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus