Retinoblastoma 1 anticorps (pSer807)
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- Antigène Voir toutes Retinoblastoma 1 (RB1) Anticorps
- Retinoblastoma 1 (RB1)
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Épitope
- pSer807
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Retinoblastoma 1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
- Purification
- Purified by Protein A.
- Immunogène
- Synthetic peptide derived from human Rb(S807), around 800-850aa (phospho S807).
- Clone
- 2D10
- Isotype
- IgG
- Top Product
- Discover our top product RB1 Anticorps primaire
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- Indications d'application
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WB 1:1000-2000
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C
- Date de péremption
- 12 months
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- Antigène
- Retinoblastoma 1 (RB1)
- Autre désignation
- Rb (RB1 Produits)
- Synonymes
- anticorps OSRC, anticorps RB, anticorps p105-Rb, anticorps pRb, anticorps pp110, anticorps Rb, anticorps Rb-1, anticorps P105-RB, anticorps PP110, anticorps RB11, anticorps zgc:154147, anticorps RB transcriptional corepressor 1, anticorps RB transcriptional corepressor like 1, anticorps retinoblastoma 1, anticorps RB1, anticorps RBL1, anticorps Rb1, anticorps rb1
- Sujet
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Nuclear Marker.The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Synonyms: RbSer780, OSRC, P105 RB, P105RB, PP105, PP110, pRb, RB 1, RB1, RB1 protein, Retinoblastoma 1 including osteosarcoma, Retinoblastoma 1, Retinoblastoma associated protein, Including osteosarcoma, Osteosarcoma, p105-Rb, Rb, RB_HUMAN, Retinoblastoma suspectibility protein, Retinoblastoma-associated protein, Retinoblastoma related osteosarcoma, Retinoblastoma susceptibility gene.
- ID gène
- 5925
- UniProt
- P06400
- Pathways
- Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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