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Retinoblastoma 1 anticorps (pSer807)

RB1 Reactivité: Humain, Souris, Rat WB, IF (cc) Hôte: Lapin Monoclonal 2D10 unconjugated
N° du produit ABIN5557520
  • Antigène Voir toutes Retinoblastoma 1 (RB1) Anticorps
    Retinoblastoma 1 (RB1)
    Épitope
    • 35
    • 27
    • 25
    • 24
    • 23
    • 21
    • 19
    • 15
    • 11
    • 10
    • 10
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer807
    Reactivité
    • 273
    • 114
    • 99
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 239
    • 36
    Lapin
    Clonalité
    • 235
    • 40
    Monoclonal
    Conjugué
    • 126
    • 19
    • 17
    • 16
    • 11
    • 10
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Retinoblastoma 1 est non-conjugé
    Application
    • 204
    • 121
    • 110
    • 79
    • 79
    • 38
    • 31
    • 28
    • 27
    • 20
    • 15
    • 8
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
    Purification
    Purified by Protein A.
    Immunogène
    Synthetic peptide derived from human Rb(S807), around 800-850aa (phospho S807).
    Clone
    2D10
    Isotype
    IgG
    Top Product
    Discover our top product RB1 Anticorps primaire
  • Indications d'application
    WB 1:1000-2000
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C
    Date de péremption
    12 months
  • Antigène
    Retinoblastoma 1 (RB1)
    Autre désignation
    Rb (RB1 Produits)
    Synonymes
    anticorps OSRC, anticorps RB, anticorps p105-Rb, anticorps pRb, anticorps pp110, anticorps Rb, anticorps Rb-1, anticorps P105-RB, anticorps PP110, anticorps RB11, anticorps zgc:154147, anticorps RB transcriptional corepressor 1, anticorps RB transcriptional corepressor like 1, anticorps retinoblastoma 1, anticorps RB1, anticorps RBL1, anticorps Rb1, anticorps rb1
    Sujet

    Nuclear Marker.The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

    Synonyms: RbSer780, OSRC, P105 RB, P105RB, PP105, PP110, pRb, RB 1, RB1, RB1 protein, Retinoblastoma 1 including osteosarcoma, Retinoblastoma 1, Retinoblastoma associated protein, Including osteosarcoma, Osteosarcoma, p105-Rb, Rb, RB_HUMAN, Retinoblastoma suspectibility protein, Retinoblastoma-associated protein, Retinoblastoma related osteosarcoma, Retinoblastoma susceptibility gene.

    ID gène
    5925
    UniProt
    P06400
    Pathways
    Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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