CTH anticorps (AA 1-405)

N° du produit ABIN560521

Détail du produit anti-CTH anticorps

Antigène: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Épitope: AA 1-405

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CTH est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Mouse monoclonal antibody raised against a full length recombinant CTH.

Séquence: MQEKDASSQG FLPHFQHFAT QAIHVGQDPE QWTSRAVVPP ISLSTTFKQG APGQHSGFEY SRSGNPTRNC LEKAVAALDG AKYCLAFASG LAATVTITHL LKAGDQIICM DDVYGGTNRY FRQVASEFGL KISFVDCSKI KLLEAAITPE TKLVWIETPT NPTQKVIDIE GCAHIVHKHG DIILVVDNTF MSPYFQRPLA LGADISMYSA TKYMNGRSDV VMGLVSVNCE SLHNRLRFLQ NSLGAVPSPI DCYLCNRGLK TLHVRMEKHF KNGMAVAQFL ESNPWVEKVI YPGLPSHPQH ELVKRQCTGC TGMVTFYIKG TLQHAEIFLK NLKLFTLAES LGGFESLAEL PAIMTHASVL KNDRDVLGIS DTLIRLSVGL EDEEDLLEDL DQALKAAHPP SGSHS

Réactivité croisée: Cobaye, Humain, Rat

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: CTH (AAH15807, 1 a.a. ~ 405 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 4E1-1B7

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-CTH (ABIN560521)

Li, Li, Du, Wang, You, Wang, Xu, Cheng, Cao, Liu, Hu: "Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter." dans: International journal of molecular sciences, Vol. 16, Issue 6, pp. 12560-77, (2015) (PubMed).

Xu, Du, Li, Xu, Wang, You, Liu, Wang, Cao, Liu, Hu: "Statins upregulate cystathionine ?-lyase transcription and H2S generation via activating Akt signaling in macrophage." dans: Pharmacological research : the official journal of the Italian Pharmacological Society, Vol. 87, pp. 18-25, (2014) (PubMed).

Ida, Sawa, Ihara, Tsuchiya, Watanabe, Kumagai, Suematsu, Motohashi, Fujii, Matsunaga, Yamamoto, Ono, Devarie-Baez, Xian, Fukuto, Akaike: "Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 21, pp. 7606-11, (2014) (PubMed).

Yang, Zhao, Ju, Mani, Cao, Puukila, Khaper, Wu, Wang: "Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2." dans: Antioxidants & redox signaling, Vol. 18, Issue 15, pp. 1906-19, (2013) (PubMed).

Mani, Li, Untereiner, Wu, Yang, Austin, Dickhout, Lhoták, Meng, Wang: "Decreased endogenous production of hydrogen sulfide accelerates atherosclerosis." dans: Circulation, Vol. 127, Issue 25, pp. 2523-34, (2013) (PubMed).

Badiei, Rivers-Auty, Ang, Bhatia: "Inhibition of hydrogen sulfide production by gene silencing attenuates inflammatory activity of LPS-activated RAW264.7 cells." dans: Applied microbiology and biotechnology, Vol. 97, Issue 17, pp. 7845-52, (2013) (PubMed).

Kasparek, Linden, Farrugia, Sarr: "Hydrogen sulfide modulates contractile function in rat jejunum." dans: The Journal of surgical research, Vol. 175, Issue 2, pp. 234-42, (2012) (PubMed).

Yang, Pei, Cao, Wang: "MicroRNA-21 represses human cystathionine gamma-lyase expression by targeting at specificity protein-1 in smooth muscle cells." dans: Journal of cellular physiology, Vol. 227, Issue 9, pp. 3192-200, (2012) (PubMed).

Yang, Li, Tang, Wu, Zhao, Cao, Xu, Wang: "Increased neointimal formation in cystathionine gamma-lyase deficient mice: role of hydrogen sulfide in ?5?1-integrin and matrix metalloproteinase-2 expression in smooth muscle cells." dans: Journal of molecular and cellular cardiology, Vol. 52, Issue 3, pp. 677-88, (2012) (PubMed).

Dufton, Natividad, Verdu, Wallace: "Hydrogen sulfide and resolution of acute inflammation: A comparative study utilizing a novel fluorescent probe." dans: Scientific reports, Vol. 2, pp. 499, (2012) (PubMed).

Wu, Teng, Yang, Wu, Wang: "Hydrogen sulfide inhibits the translational expression of hypoxia-inducible factor-1?." dans: British journal of pharmacology, Vol. 167, Issue 7, pp. 1492-505, (2012) (PubMed).

Fu, Zhang, Yang, Wang: "Is cystathionine gamma-lyase protein expressed in the heart?" dans: Biochemical and biophysical research communications, Vol. 428, Issue 4, pp. 469-74, (2012) (PubMed).

Holwerda, Bos, Rajakumar, Ris-Stalpers, van Pampus, Timmer, Erwich, Faas, van Goor, Lely: "Hydrogen sulfide producing enzymes in pregnancy and preeclampsia." dans: Placenta, Vol. 33, Issue 6, pp. 518-21, (2012) (PubMed).

Yang, Pei, Teng, Cao, Wang: "Specificity protein-1 as a critical regulator of human cystathionine gamma-lyase in smooth muscle cells." dans: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26450-60, (2011) (PubMed).

Li, Mao, Hei, Zhang, Wen, Zhang, Qiu, Qiao: "Protective role of hydrogen sulfide against noise-induced cochlear damage: a chronic intracochlear infusion model." dans: PLoS ONE, Vol. 6, Issue 10, pp. e26728, (2011) (PubMed).

Martin, McKnight, Dicay, Coffin, Ferraz, Wallace: "Hydrogen sulphide synthesis in the rat and mouse gastrointestinal tract." dans: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, Vol. 42, Issue 2, pp. 103-9, (2010) (PubMed).

Feng, Chen, Zhao, Tang, Jiang, Geng: "Hydrogen sulfide from adipose tissue is a novel insulin resistance regulator." dans: Biochemical and biophysical research communications, Vol. 380, Issue 1, pp. 153-9, (2009) (PubMed).

Wallace, Vong, McKnight, Dicay, Martin: "Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats." dans: Gastroenterology, Vol. 137, Issue 2, pp. 569-78, 578.e1, (2009) (PubMed).

Fu, Liu, Geng, Fang, Tang: "Hydrogen sulfide protects rat lung from ischemia-reperfusion injury." dans: Life sciences, Vol. 82, Issue 23-24, pp. 1196-202, (2008) (PubMed).

Wallace, Dicay, McKnight, Martin: "Hydrogen sulfide enhances ulcer healing in rats." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 14, pp. 4070-6, (2007) (PubMed).

Détails sur CTH

Antigène: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Autre désignation: CTH (CTH Produits)

Synonymes: anticorps DYT17, anticorps DYT18, anticorps DYT9, anticorps EIG12, anticorps GLUT, anticorps GLUT1, anticorps GLUT1DS, anticorps HTLVR, anticorps PED, anticorps wu:fb48e03, anticorps wu:fb58d08, anticorps zgc:66001, anticorps zgc:85785, anticorps CTH, anticorps 0610010I13Rik, anticorps AI314617, anticorps BC019483, anticorps CSE, anticorps Cys3, anticorps cysA, anticorps SCQ11.03c, anticorps DDBDRAFT_0190313, anticorps DDBDRAFT_0191318, anticorps DDB_0190313, anticorps DDB_0191318, anticorps H, anticorps MGC75946, anticorps cystathionine gamma-lyase, anticorps solute carrier family 2 member 1, anticorps cystathionase (cystathionine gamma-lyase), anticorps cystathionine gamma-lyase L homeolog, anticorps CTH, anticorps SLC2A1, anticorps cth, anticorps Cth, anticorps SCO3920, anticorps mlr1566, anticorps TA_RS00415, anticorps MAP_RS15640, anticorps SPO3344, anticorps CNN01730, anticorps Mmcs_1928, anticorps RHA1_RS31820, anticorps HNE_1212, anticorps MAV_3867, anticorps MSMEG_2394, anticorps Mvan_2142, anticorps SACE_6136, anticorps Mflv_4220, anticorps cysA, anticorps cth.L

Sujet: Full Gene Name: cystathionase (cystathionine gamma-lyase)
Synonyms: MGC9471

ID gène: 1491

Pathways: ER-Nucleus Signaling, L'effet Warburg