Glutaminase anticorps (AA 580-669)

N° du produit ABIN561056

L’anticorps Souris Monoclonal anti-Glutaminase a été validé pour WB, ELISA et IF. Il convient pour détecter Glutaminase dans des échantillons de Humain. Il y a 4+ publications disponibles.

Aperçu rapide pour Glutaminase anticorps (AA 580-669) (ABIN561056)

Antigène: Glutaminase (GLS)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Glutaminase est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 5C4

Détail du produit anti-Glutaminase anticorps

Épitope: AA 580-669

Fonction: Mouse monoclonal antibody raised against a partial recombinant GLS.

Séquence: EQRDYDSRTA LHVAAAEGHV EVVKFLLEAC KVNPFPKDRW NNTPMDEALH FGHHDVFKIL QEYQVQYTPQ GDSDNGKENQ TVHKNLDGLL

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: GLS (NP_055720, 580 a.a. ~ 669 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-Glutaminase (ABIN561056)

Reynolds, Lane, Robertson, Kemp, Liu, Hill, Dean, Clem: "Control of glutamine metabolism by the tumor suppressor Rb." dans: Oncogene, Vol. 33, Issue 5, pp. 556-66, (2014) (PubMed).

Hida, Mouri, Ando, Mori, Mamiya, Iwamoto, Ozaki, Yamada, Nabeshima, Noda: "Combination of neonatal PolyI:C and adolescent phencyclidine treatments is required to induce behavioral abnormalities with overexpression of GLAST in adult mice." dans: Behavioural brain research, Vol. 258, pp. 34-42, (2013) (PubMed).

Cassago, Ferreira, Ferreira, Fornezari, Gomes, Greene, Pereira, Garratt, Dias, Ambrosio: "Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 4, pp. 1092-7, (2012) (PubMed).

Unterluggauer, Mazurek, Lener, Hütter, Eigenbrodt, Zwerschke, Jansen-Dürr: "Premature senescence of human endothelial cells induced by inhibition of glutaminase." dans: Biogerontology, Vol. 9, Issue 4, pp. 247-59, (2008) (PubMed).

Détails sur Glutaminase

Antigène: Glutaminase (GLS)

Autre désignation: GLS

Sujet: Full Gene Name: glutaminase
Synonyms: AAD20,DKFZp686O15119,FLJ10358,GLS1,KIAA0838

ID gène: 2744

NCBI Accession: NM_014905

Pathways: Feeding Behaviour, Dicarboxylic Acid Transport, L'effet Warburg