eIF4EBP1 anticorps (pSer65)
Aperçu rapide pour eIF4EBP1 anticorps (pSer65) (ABIN5611114)
Antigène
Voir toutes eIF4EBP1 (EIF4EBP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- pSer65
-
Fonction
- Phospho-4E-BP1 (Ser65) Antibody
-
Purification
- Purified antibody
-
Immunogène
- Synthesized peptide of human Phospho-4E-BP1 (Ser65).
-
Isotype
- IgG1
-
-
-
-
Indications d'application
-
ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/100 - 1/500
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
- eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
-
Autre désignation
- 4E-BP1
-
Sujet
-
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
-
Poids moléculaire
- 12.6 kDa
-
ID gène
- 1978
-
UniProt
- Q13541
-
Pathways
- Signalisation MAPK, Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Regulation of Cell Size, BCR Signaling
Antigène
-