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BTRC anticorps (AA 24-151)

BTRC Reactivité: Humain WB, ELISA, IHC, ICC, FACS, Neut Hôte: Souris Monoclonal 4C5D8 unconjugated
N° du produit ABIN5611131
  • Antigène Voir toutes BTRC Anticorps
    BTRC (beta-Transducin Repeat Containing (BTRC))
    Épitope
    • 10
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 24-151
    Reactivité
    • 44
    • 16
    • 12
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 44
    • 4
    Souris
    Clonalité
    • 44
    • 4
    Monoclonal
    Conjugué
    • 21
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BTRC est non-conjugé
    Application
    • 28
    • 23
    • 20
    • 16
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human BTRC (AA: 24-151) expressed in E. coli.
    Clone
    4C5D8
    Isotype
    IgG1
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Antigène
    BTRC (beta-Transducin Repeat Containing (BTRC))
    Autre désignation
    BTRC (BTRC Produits)
    Synonymes
    anticorps BTRC, anticorps Beta-TrCP, anticorps betaTrCP, anticorps btrcp, anticorps btrcp1, anticorps fbw1a, anticorps fbxw1, anticorps fbxw1a, anticorps fwd1, anticorps btrc, anticorps beta-TrCP, anticorps BETA-TRCP, anticorps FBW1A, anticorps FBXW1, anticorps FBXW1A, anticorps FWD1, anticorps bTrCP, anticorps bTrCP1, anticorps beta-TrCP1, anticorps btrc-a, anticorps Beta-Trcp1, anticorps Fbw1a, anticorps HOS, anticorps Slimb, anticorps b-TrCP, anticorps mKIAA4123, anticorps beta-transducin repeat containing E3 ubiquitin protein ligase, anticorps beta-transducin repeat containing, anticorps beta-TrCP, anticorps beta-transducin repeat containing E3 ubiquitin protein ligase S homeolog, anticorps beta-transducin repeat containing protein, anticorps BTRC, anticorps btrc, anticorps LOC100634006, anticorps Btrc, anticorps btrc.S
    Sujet

    Description: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class, in addition to an F-box, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6.

    Aliases: FWD1, FBW1A, FBXW1, bTrCP, FBXW1A, bTrCP1, betaTrCP, BETA-TRCP

    Poids moléculaire
    68.9 kDa
    ID gène
    8945
    HGNC
    8945
    Pathways
    Cycle Cellulaire, Signalisation Hedgehog
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