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Metabotropic Glutamate Receptor 1 anticorps (C-Term)

GRM1 Reactivité: Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6658163
  • Antigène Voir toutes Metabotropic Glutamate Receptor 1 (GRM1) Anticorps
    Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))
    Épitope
    • 15
    • 15
    • 10
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 64
    • 46
    • 44
    • 15
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Rat
    Hôte
    • 76
    • 18
    • 2
    • 1
    Lapin
    Clonalité
    • 72
    • 25
    Polyclonal
    Conjugué
    • 44
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Metabotropic Glutamate Receptor 1 est non-conjugé
    Application
    • 50
    • 30
    • 25
    • 25
    • 18
    • 17
    • 14
    • 14
    • 13
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
     Réactivité croisée
    Souris, Rat (Rattus)
    Réactivité croisée (Details)
    Cross reactivity from other sources has not been determined.
    Purification
    Anti-mGluR1a antibodies are affinity purified from monospecific antiserum by immunoaffinity purification. Immunolabeling blocked by preadsorption of antibody with the peptide used to generate the antibody. This antibody is directed against rat mGluR1a. Reactivity is expected from mouse.
    Immunogène

    Immunogen: Anti-mGluR1a Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.

    Immunogen Type: Peptide

    Isotype
    IgG
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    Discover our top product GRM1 Anticorps primaire
  • Indications d'application

    Immunohistochemistry Dilution: 1:500

    Application Note: Anti-mGluR1a antibody is suitable for use in Western Blotting and IHC. Expect a band of approximately 125 kDa monomer and 250 kDa mGluR1a dimer in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.

    Western Blot Dilution: 1:1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
  • Antigène
    Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))
    Autre désignation
    mGluR1a (GRM1 Produits)
    Synonymes
    anticorps fj39d05, anticorps wu:fj39d05, anticorps si:ch211-51a19.1, anticorps Glura, anticorps mGlutR, anticorps GB18621, anticorps GPRC1A, anticorps MGLU1, anticorps MGLUR1, anticorps SCAR13, anticorps 4930455H15Rik, anticorps ENSMUSG00000075319, anticorps Gm10828, anticorps Gprc1a, anticorps mGluR1, anticorps nmf373, anticorps rcw, anticorps wobl, anticorps glutamate metabotropic receptor 1, anticorps glutamate receptor, metabotropic 1a, anticorps metabotropic glutamate receptor 1, anticorps glutamate receptor, metabotropic 1, anticorps GRM1, anticorps grm1a, anticorps mGlutR1, anticorps Grm1
    Sujet

    Synonyms: mGluR1, Metabotropic Glutamate Receptor 1a

    Background: mGluR1a antibodies detect GluR1a. GluR1a is the metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse. Group I metabotropic glutamate receptors (consisting of mGluR1 and mGluR5) are G-protein-coupled neurotransmitter receptors that are localized in the perisynaptic region of the postsynaptic membrane. When activated, Group I mGluRs lead to stimulation of phospholipase and activation of Protein Kinase C. In contrast, activation of Group II metabotropic receptors (mGluR2 and mGluR3) leads to inhibition of adenylate cyclase. The mGluR1 receptor may also be critically involved in limiting the deleterious effects of excitotoxicity. Therefore, mGluR1a antibody is ideal for investigators involved in neuronal plasticitiy, cell signaling and neuroscience.

    Gene Name: GRM1

    ID gène
    24414
    UniProt
    P23385
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