Metabotropic Glutamate Receptor 1 anticorps (C-Term)
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- Antigène Voir toutes Metabotropic Glutamate Receptor 1 (GRM1) Anticorps
- Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))
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Épitope
- C-Term
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Metabotropic Glutamate Receptor 1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Réactivité croisée
- Souris, Rat (Rattus)
- Réactivité croisée (Details)
- Cross reactivity from other sources has not been determined.
- Purification
- Anti-mGluR1a antibodies are affinity purified from monospecific antiserum by immunoaffinity purification. Immunolabeling blocked by preadsorption of antibody with the peptide used to generate the antibody. This antibody is directed against rat mGluR1a. Reactivity is expected from mouse.
- Immunogène
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Immunogen: Anti-mGluR1a Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
Immunogen Type: Peptide
- Isotype
- IgG
- Top Product
- Discover our top product GRM1 Anticorps primaire
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- Indications d'application
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Immunohistochemistry Dilution: 1:500
Application Note: Anti-mGluR1a antibody is suitable for use in Western Blotting and IHC. Expect a band of approximately 125 kDa monomer and 250 kDa mGluR1a dimer in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.
Western Blot Dilution: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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- Antigène
- Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))
- Autre désignation
- mGluR1a (GRM1 Produits)
- Synonymes
- anticorps fj39d05, anticorps wu:fj39d05, anticorps si:ch211-51a19.1, anticorps Glura, anticorps mGlutR, anticorps GB18621, anticorps GPRC1A, anticorps MGLU1, anticorps MGLUR1, anticorps SCAR13, anticorps 4930455H15Rik, anticorps ENSMUSG00000075319, anticorps Gm10828, anticorps Gprc1a, anticorps mGluR1, anticorps nmf373, anticorps rcw, anticorps wobl, anticorps glutamate metabotropic receptor 1, anticorps glutamate receptor, metabotropic 1a, anticorps metabotropic glutamate receptor 1, anticorps glutamate receptor, metabotropic 1, anticorps GRM1, anticorps grm1a, anticorps mGlutR1, anticorps Grm1
- Sujet
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Synonyms: mGluR1, Metabotropic Glutamate Receptor 1a
Background: mGluR1a antibodies detect GluR1a. GluR1a is the metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse. Group I metabotropic glutamate receptors (consisting of mGluR1 and mGluR5) are G-protein-coupled neurotransmitter receptors that are localized in the perisynaptic region of the postsynaptic membrane. When activated, Group I mGluRs lead to stimulation of phospholipase and activation of Protein Kinase C. In contrast, activation of Group II metabotropic receptors (mGluR2 and mGluR3) leads to inhibition of adenylate cyclase. The mGluR1 receptor may also be critically involved in limiting the deleterious effects of excitotoxicity. Therefore, mGluR1a antibody is ideal for investigators involved in neuronal plasticitiy, cell signaling and neuroscience.
Gene Name: GRM1
- ID gène
- 24414
- UniProt
- P23385
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