Axin anticorps (AA 546-752)

N° du produit ABIN5611199

Cet anticorps Souris Monoclonal détecte spécifiquement Axin dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Axin anticorps (AA 546-752) (ABIN5611199)

Antigène: Axin (AXIN1) (Axin 1 (AXIN1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Axin est non-conjugé

Application: ELISA

Clone: 4F10G1

Détail du produit anti-Axin anticorps

Épitope: AA 546-752

Fonction: AXIN1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human 4F10G1 (AA: 546-752) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur Axin

Antigène: Axin (AXIN1) (Axin 1 (AXIN1))

Autre désignation: AXIN1

Sujet: This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 95.6 kDa

ID gène: 8312

UniProt: O15169

Pathways: Signalisation WNT, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling