Diazepam Binding Inhibitor anticorps (AA 2-187)

N° du produit ABIN5647032

Cet anticorps Lapin Polyclonal détecte spécifiquement Diazepam Binding Inhibitor dans WB, FACS et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour Diazepam Binding Inhibitor anticorps (AA 2-187) (ABIN5647032)

Antigène: Diazepam Binding Inhibitor (DBI)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Diazepam Binding Inhibitor est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Diazepam Binding Inhibitor anticorps

Épitope: AA 2-187

Purification: Antigen affinity purified

Immunogène: A human recombinant protein corresponding to amino acids S2-I87 was used as the immunogen for the DBI antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the DBI antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL,Flow cytometry: 1-3 μg/10^6 cells

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the DBI antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Diazepam Binding Inhibitor

Antigène: Diazepam Binding Inhibitor (DBI)

Autre désignation: DBI / Diazepam Binding Inhibitor

Sujet: Acyl-CoA-binding protein, also called Diazepam binding inhibitor, is a protein that in humans is encoded by the DBI gene. This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

UniProt: P07108