Hexokinase 2 anticorps (AA 460-497)

N° du produit ABIN5647143

Cet anticorps Lapin Polyclonal détecte spécifiquement Hexokinase 2 dans WB, FACS et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Hexokinase 2 anticorps (AA 460-497) (ABIN5647143)

Antigène: Hexokinase 2 (HK2)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Hexokinase 2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Hexokinase 2 anticorps

Épitope: AA 460-497

Fonction: Hexokinase II Antibody

Purification: Antigen affinity

Immunogène: Amino acids 460-497 (AYRLADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMER-human) were used as the immunogen for the Hexokinase II antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Hexokinase II antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Hexokinase II antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Hexokinase 2

Antigène: Hexokinase 2 (HK2)

Autre désignation: Hexokinase II

Sujet: Hexokinase II, also known as HK2, is an enzyme which in humans is encoded by the HK2 gene on chromosome 2. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase ii/2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

UniProt: P52789

Pathways: Signalisation PI3K-Akt, Carbohydrate Homeostasis, L'effet Warburg