KIT Ligand anticorps

N° du produit ABIN5647180

L’anticorps Lapin Polyclonal anti-KIT Ligand a été validé pour WB, IHC (p) et ELISA (Capture). Il convient pour détecter KIT Ligand dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour KIT Ligand anticorps (ABIN5647180)

Antigène: KIT Ligand (KITLG)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIT Ligand est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA (Capture)

Détail du produit anti-KIT Ligand anticorps

Purification: Antigen affinity purified

Immunogène: A recombinant human protein corresponding to amino acids E26-A190 was used as the immunogen for the SCF antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the SCF antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,ELISA (Capture, human recombinant protein): 0.1-0.5 μg/mL (BSA-free format available)

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the SCF antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur KIT Ligand

Antigène: KIT Ligand (KITLG)

Autre désignation: SCF / KITLG

Sujet: Stem Cell Factor (also known as SCF, kit-ligand, KL, or steel factor) is a cytokine that binds to the c-Kit receptor (CD117). The SCF gene is mapped to 12q21.32. SCF can exist both as a transmembrane protein and a soluble protein. This cytokine plays an important role in hematopoiesis (formation of blood cells), spermatogenesis, and melanogenesis. SCF may be used along with other cytokines to culture HSCs and hematopoietic progenitors. The expansion of these cells ex-vivo (outside the body) would allow advances in bone-marrow transplantation, in which HSCs are transferred to a patient to re-establish blood formation. One of the problems of injecting SCF for therapeutic purposes is that SCF activates mast cells. The injection of SCF has been shown to cause allergic-like symptoms and the proliferation of mast cells and melanocytes.

UniProt: P21583

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway