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ASXL1 anticorps

ASXL1 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5647693
  • Antigène Voir toutes ASXL1 Anticorps
    ASXL1 (Additional Sex Combs Like 1 (ASXL1))
    Reactivité
    • 27
    • 24
    • 1
    Humain, Souris
    Hôte
    • 29
    • 2
    Lapin
    Clonalité
    • 29
    • 2
    Polyclonal
    Conjugué
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ASXL1 est non-conjugé
    Application
    • 22
    • 16
    • 14
    • 14
    • 14
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Antigen affinity purified
    Immunogène
    Amino acids KKERTWAEAARLVLENYSDAPMTPKQILQVIEAE were used as the immunogen for the ASXL1 antibody.
    Isotype
    IgG
    Top Product
    Discover our top product ASXL1 Anticorps primaire
  • Indications d'application
    Optimal dilution of the ASXL1 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Stock
    -20 °C
    Stockage commentaire
    After reconstitution, the ASXL1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Antigène
    ASXL1 (Additional Sex Combs Like 1 (ASXL1))
    Autre désignation
    ASXL1 (ASXL1 Produits)
    Synonymes
    anticorps asxl1, anticorps MGC83850, anticorps mKIAA0978, anticorps BOPS, anticorps MDS, anticorps additional sex combs like 1, transcriptional regulator L homeolog, anticorps additional sex combs like 1, transcriptional regulator, anticorps additional sex combs like 1, anticorps asxl1.L, anticorps ASXL1, anticorps asxl1, anticorps Asxl1
    Sujet
    Putative Polycomb group protein ASXL1 is a protein that in humans is encoded by the ASXL1 gene. This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants.
    UniProt
    Q8IXJ9
    Pathways
    Retinoic Acid Receptor Signaling Pathway
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