RNF139 anticorps (AA 565-664)

N° du produit ABIN564886

Cet anticorps Souris Polyclonal détecte spécifiquement RNF139 dans WB et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 4+ publications.

Aperçu rapide pour RNF139 anticorps (AA 565-664) (ABIN564886)

Antigène: RNF139 (Ring Finger Protein 139 (RNF139))

Reactivité: Humain

Hôte: Souris

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF139 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RNF139 anticorps

Épitope: AA 565-664

Fonction: Mouse polyclonal antibody raised against a partial recombinant RNF139.

Séquence: HYFHALCLRK WLYIQDTCPM CHQKVYIEDD IKDNSNVSNN NGFIPPNETP EEAVREAAAE SDRELNEDDS TDCDDDVQRE RNGVIQHTGA AAEEFNDDTD

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: RNF139 (NP_009149, 565 a.a. ~ 664 a.a) partial recombinant protein with GST tag.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 50 % glycerol

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-RNF139 (ABIN564886)

Lee, Brauweiler, Rudolph, Hooper, Drabkin, Gemmill: "The TRC8 ubiquitin ligase is sterol regulated and interacts with lipid and protein biosynthetic pathways." dans: Molecular cancer research : MCR, Vol. 8, Issue 1, pp. 93-106, (2010) (PubMed).

Irisawa, Inoue, Ozawa, Mori, Sato et al.: "The sterol-sensing endoplasmic reticulum (ER) membrane protein TRC8 hampers ER to Golgi transport of sterol regulatory element-binding protein-2 (SREBP-2)/SREBP cleavage-activated protein and reduces ..." dans: The Journal of biological chemistry, Vol. 284, Issue 42, pp. 28995-9004, (2009) (PubMed).

Stagg, Thomas, van den Boomen, Wiertz, Drabkin, Gemmill, Lehner: "The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER." dans: The Journal of cell biology, Vol. 186, Issue 5, pp. 685-92, (2009) (PubMed).

Brauweiler, Lorick, Lee, Tsai, Chan, Weissman, Drabkin, Gemmill: "RING-dependent tumor suppression and G2/M arrest induced by the TRC8 hereditary kidney cancer gene." dans: Oncogene, Vol. 26, Issue 16, pp. 2263-71, (2007) (PubMed).

Détails sur RNF139

Antigène: RNF139 (Ring Finger Protein 139 (RNF139))

Autre désignation: RNF139

Sujet: Full Gene Name: ring finger protein 139
Synonyms: HRCA1,MGC31961,RCA1,TRC8

ID gène: 11236

NCBI Accession: NM_007218