SIRT1 anticorps (AA 456-555)

N° du produit ABIN565071

Cet anticorps anti-SIRT1 est un anticorps Souris Monoclonal détectant SIRT1 dans WB, ELISA, IF et IHC (p). Adapté pour Humain. Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour SIRT1 anticorps (AA 456-555) (ABIN565071)

Antigène: SIRT1 (Sirtuin 1 (SIRT1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIRT1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 7B7

Détail du produit anti-SIRT1 anticorps

Épitope: AA 456-555

Fonction: Mouse monoclonal antibody raised against a partial recombinant SIRT1.

Séquence: NRYIFHGAEV YSDSEDDVLS SSSCGSNSDS GTCQSPSLEE PMEDESEIEE FYNGLEDEPD VPERAGGAGF GTDGDDQEAI NEAISVKQEV TDMNYPSNKS

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: SIRT1 (AAH12499, 456 a.a. ~ 555 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-SIRT1 (ABIN565071)

Kok, Lin, Hou, Hong, Chang, Hsiao, Wang, Lai, Lin: "Simvastatin inhibits cysteine-rich protein 61 expression in rheumatoid arthritis synovial fibroblasts through the regulation of sirtuin-1/FoxO3a signaling." dans: Arthritis and rheumatism, Vol. 65, Issue 3, pp. 639-49, (2013) (PubMed).

Østrup, Hyttel, Klærke, Collas: "Remodeling of ribosomal genes in somatic cells by Xenopus egg extract." dans: Biochemical and biophysical research communications, Vol. 412, Issue 3, pp. 487-93, (2011) (PubMed).

Hiraike, Wada-Hiraike, Nakagawa, Koyama, Miyamoto, Sone, Tanikawa, Tsuruga, Nagasaka, Matsumoto, Oda, Shoji, Fukuhara, Saji, Nakagawa, Kato, Yano, Taketani: "Identification of DBC1 as a transcriptional repressor for BRCA1." dans: British journal of cancer, Vol. 102, Issue 6, pp. 1061-7, (2010) (PubMed).

Détails sur SIRT1

Antigène: SIRT1 (Sirtuin 1 (SIRT1))

Autre désignation: SIRT1

Sujet: Full Gene Name: sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)
Synonyms: SIR2L1

ID gène: 23411

Pathways: Signalisation MAPK, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling