TARDBP anticorps (AA 1-260)

N° du produit ABIN565079

L’anticorps Souris Polyclonal anti-TARDBP a été validé pour WB et ELISA. Il convient pour détecter TARDBP dans des échantillons de Humain. Il y a 5+ publications disponibles.

Aperçu rapide pour TARDBP anticorps (AA 1-260) (ABIN565079)

Antigène: TARDBP (TAR DNA Binding Protein (TARDBP))

Reactivité: Humain

Hôte: Souris

Clonalité: Polyclonal

Conjugué: Cet anticorp TARDBP est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TARDBP anticorps

Épitope: AA 1-260

Fonction: Mouse polyclonal antibody raised against a partial recombinant TARDBP.

Séquence: MSEYIRVTED ENDEPIEIPS EDDGTVLLST VTAQFPGACG LRYRNPVSQC MRGVRLVEGI LHAPDAGWGN LVYVVNYPKD NKRKMDETDA SSAVKVKRAV QKTSDLIVLG LPWKTTEQDL KEYFSTFGEV LMVQVKKDLK TGHSKGFGFV RFTEYETQVK VMSQRHMIDG RWCDCKLPNS KQSQDEPLRS RKVFVGRCTE DMTEDELREF FSQYGDVMDV FIPKPFRAFA FVTFADDQIA QSLCGEDLII KGISVHISNA

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: TARDBP (NP_031401.1, 1 a.a. ~ 260 a.a) partial recombinant protein with GST tag.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 50 % glycerol

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-TARDBP (ABIN565079)

Ayala, Granado-Serrano, Cacabelos, Naudí, Ilieva, Boada, Caraballo-Miralles, Lladó, Ferrer, Pamplona, Portero-Otin: "Cell stress induces TDP-43 pathological changes associated with ERK1/2 dysfunction: implications in ALS." dans: Acta neuropathologica, Vol. 122, Issue 3, pp. 259-70, (2011) (PubMed).

Tatom, Wang, Dayton, Skalli, Hutton, Dickson, Klein: "Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression." dans: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 17, Issue 4, pp. 607-13, (2009) (PubMed).

Schwab, Arai, Hasegawa, Akiyama, Yu, McGeer: "TDP-43 pathology in familial British dementia." dans: Acta neuropathologica, Vol. 118, Issue 2, pp. 303-11, (2009) (PubMed).

Johnson, McCaffery, Lindquist, Gitler: "A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 17, pp. 6439-44, (2008) (PubMed).

Schwab, Arai, Hasegawa, Yu, McGeer: "Colocalization of transactivation-responsive DNA-binding protein 43 and huntingtin in inclusions of Huntington disease." dans: Journal of neuropathology and experimental neurology, Vol. 67, Issue 12, pp. 1159-65, (2008) (PubMed).

Détails sur TARDBP

Antigène: TARDBP (TAR DNA Binding Protein (TARDBP))

Autre désignation: TARDBP

Sujet: Full Gene Name: TAR DNA binding protein
Synonyms: ALS10,TDP-43

ID gène: 23435

NCBI Accession: NM_007375

Pathways: Positive Regulation of Peptide Hormone Secretion