CD14 anticorps
Aperçu rapide pour CD14 anticorps (ABIN5663315)
Antigène
Voir toutes CD14 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Mouse CD14
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Purification
- unpurified antiserum
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Immunogène
- recombinant human LBP
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with bidistilled water
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Buffer
- PBS, pH 7.25
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Agent conservateur
- Without preservative
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Stock
- -20 °C,-80 °C
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- CD14
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Autre désignation
- CD14
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Sujet
- Background: mCD14 antiserum represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.
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Poids moléculaire
- ~58kDa
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ID gène
- 12475
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NCBI Accession
- NP_033971
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UniProt
- P10810
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Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Antigène
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