Recombinant CD40L (Ruplizumab Biosimilar) anticorps

N° du produit ABIN5668047

Cet anticorps Lapin Chimeric détecte spécifiquement CD40L (Ruplizumab Biosimilar) dans FACS, WB et BR. Il présente une réactivité envers Humain.

Aperçu rapide pour Recombinant CD40L (Ruplizumab Biosimilar) anticorps (ABIN5668047)

Antigène: CD40L (Ruplizumab Biosimilar) (CD40LG (Ruplizumab Biosimilar))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CD40L (Ruplizumab Biosimilar) est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Blocking Reagent (BR)

Clone: Hu5c8

Détail du produit anti-CD40L (Ruplizumab Biosimilar) anticorps

Fonction: Anti-CD40L [hu5c8 (Ruplizumab)], Rabbit IgG, kappa

Specificité: The antibody binds to CD40L with an IC50 of 0.845 μg/mL.

Attributs du produit:

Original Species of Ab: Human

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Pureté: > 98 % as determined by SDS-PAGE

niveau d'endotoxine: Endotoxin is < 1.0 EU/mg as determined by the LAL method

Immunogène: Human CD40L

Isotype: IgG kappa

Information d'application

Indications d'application: The antibody binds specifically to CD40L, a surface receptor expressed on activated T cells which acts as a costimulatory molecule to trigger immune responses. The antibody neutralises CD40L function, as it blocks the interaction between CD40 and CD40L. When injected into cynomolgus monkeys, the original therapeutic antibody was found to have a T1/2 of 531 ± 155 hours.

Commentaires:

NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD40L (Ruplizumab Biosimilar)

Antigène: CD40L (Ruplizumab Biosimilar) (CD40LG (Ruplizumab Biosimilar))

Autre désignation: CD40L (Ruplizumab Biosimilar)

Classe de substances: Biosimilar

Sujet: CD154, CD40 ligand, tumour necrosis factor ligand superfamily member 5, TNFSF5, tumour necrosis factor related activation protein, TRAP

UniProt: P29965