CHRNB3 anticorps (N-Term)

N° du produit ABIN5671353

Cet anticorps Lapin Polyclonal détecte spécifiquement CHRNB3 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Souris, Chien, Cobaye, Boeuf (Vache), Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour CHRNB3 anticorps (N-Term) (ABIN5671353)

Antigène: CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))

Reactivité: Humain, Rat, Souris, Chien, Cobaye, Boeuf (Vache), Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRNB3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CHRNB3 anticorps

Épitope: N-Term

Fonction: CHRNB3 Antibody - N-terminal region

Séquence: QGYQKWVRPV LHSNDTIKVY FGLKISQLVD VDEKNQLMTT NVWLKQEWTD

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against ACHB3. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ACHB3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34971-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CHRNB3

Antigène: CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))

Autre désignation: CHRNB3

Sujet:

Background Information: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1 (MIM 100690), they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten, 1997 [PubMed 9009220]). Elliott et al. (1996) [PubMed 8906617] stated that the proposed structure for each subunit is a conserved N-terminal extracellular domain followed by 3 conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region.[supplied by OMIM, Apr 2010]

Gene Name: cholinergic receptor nicotinic beta 3 subunit

Protein Name: neuronal acetylcholine receptor subunit beta-3

Poids moléculaire: 50kDa

ID gène: 1142

NCBI Accession: NP_000740

UniProt: Q05901