Complement Factor B anticorps (N-Term)

N° du produit ABIN5674038

Détail du produit anti-Complement Factor B anticorps

Antigène: Complement Factor B (CFB)

Épitope: N-Term

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Complement Factor B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Specificité: Recognizes the 30kD Ba fragment of 90kD human complement factor B, present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit), leaving the 63 kD Bb subunit associated with C3b, forming C3 convertase. Subunit Ba inhibits lymphocyte proliferation. Conversely, subunit Bb is involved in the proliferation of preactivated B lymphocytes. Binds both the Ba fragment and the whole protein so is not suitable for all ELISA applications.

Purification: Protein A purified

Immunogène: Purified human complement factor b.

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA, Flo, Func, IHC, IHC-Fr, WB

Usage: ELISA: LS-C44996 binds both the Ba fragment and the whole protein so is not suitable for all ELISA applications.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Borate buffered saline,  pH 8.2 - 8.4, 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: avoid freeze thaw cycles. Store undiluted.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.

Détails sur Complement Factor B

Antigène: Complement Factor B (CFB)

Autre désignation: CFB / Complement Factor B (CFB Produits)

Synonymes: anticorps AHUS4, anticorps BF, anticorps BFD, anticorps CFAB, anticorps FB, anticorps FBI12, anticorps GBG, anticorps H2-Bf, anticorps PBF2, anticorps bf, anticorps Bf-1, anticorps Brre-Bf, anticorps zgc:114032, anticorps Bf, anticorps Sp152, anticorps bfb-A, anticorps Bf B, anticorps LOC397725, anticorps bf/c2, anticorps CFB, anticorps AI195813, anticorps AI255840, anticorps B, anticorps C2, anticorps Fb, anticorps Da1-24, anticorps complement factor B, anticorps complement factor B S homeolog, anticorps complement factor B L homeolog, anticorps CFB, anticorps cfb, anticorps bf, anticorps cfb.S, anticorps cfb.L, anticorps bf/c2, anticorps LOC100555981, anticorps Cfb

Sujet: Name/Gene ID: CFB
Subfamily: Serine S1
Family: Protease

Synonyms: CFB, AHUS4, B-factor, properdin, C3/C5 convertase, CFAB, C3 proaccelerator, C3 proactivator, Complement factor B, Complement protein Factor B, Glycine-rich beta-glycoprotein, GBG, Factor B, FB, Glycine-rich beta glycoprotein, PBF2, BF, BFD, FBI12, H2-Bf, Properdin factor B

ID gène: 629

UniProt: P00751

Pathways: Système du Complément, Proton Transport, Ribonucleoside Biosynthetic Process