HRH3 anticorps (AA 281-380)
Aperçu rapide pour HRH3 anticorps (AA 281-380) (ABIN5675026)
Antigène
Voir toutes HRH3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 281-380
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Réactivité croisée
- Humain, Souris, Rat
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Homologie
- Cow,Sheep,Horse
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human HRH3
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- HRH3 (Histamine Receptor H3 (HRH3))
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Autre désignation
- HRH3
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Sujet
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Synonyms: Histamine H3 receptor, HRH3, H3R, HH3R, G-protein coupled receptor 97, GPCR97
Background: The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization. Does not bind to cimetidine and tripolidine. Shows modest affinity for thioperamide, imetit, N-alpha-methylhistamine and R--alpha-methylhistamine. Isoform 4 is unable to bind to iodoproxyfan while isoforms 1 and 3 bind it with high affinity.
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ID gène
- 11255
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UniProt
- Q9Y5N1
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Pathways
- cAMP Metabolic Process, Feeding Behaviour
Antigène
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