ATF3 anticorps

N° du produit ABIN5676162

Cet anticorps Souris Monoclonal détecte spécifiquement ATF3 dans ICC et DB. Il présente une réactivité envers Humain.

Aperçu rapide pour ATF3 anticorps (ABIN5676162)

Antigène: ATF3 (Activating Transcription Factor 3 (ATF3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ATF3 est non-conjugé

Application: Immunocytochemistry (ICC), Dot Blot (DB)

Clone: 44C3a

Détail du produit anti-ATF3 anticorps

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogène: ATF3 antibody was raised in mouse using recombinant Human Activating Transcription Factor 3

Isotype: IgG1

Information d'application

Indications d'application: ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: ATF3 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Détails sur ATF3

Antigène: ATF3 (Activating Transcription Factor 3 (ATF3))

Autre désignation: ATF3

Sujet: Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive elementbinding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. Synonyms: Monoclonal ATF3 antibody, Anti-ATF3 antibody, Cyclic AMP-dependent transcription factor ATF-3 antibody.

Pathways: Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response