POLD2 anticorps

N° du produit ABIN567777

Détail du produit anti-POLD2 anticorps

Antigène: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Reactivité: Humain, Rat, Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp POLD2 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts with DNA polymerase delta p50 small subunit (50 kDa) by Western blotting.

Purification: Protein-G Agarose Chromatography of hybridoma supernatant.

Immunogène: Recombinant full length His-Human p50

Clone: 7B4

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 50 % Glycerol without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur POLD2

Antigène: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Autre désignation: POLD2 (POLD2 Produits)

Synonymes: anticorps 50kDa, anticorps p50, anticorps po1D2, anticorps cdc1, anticorps si:dz150f13.3, anticorps zgc:55633, anticorps zgc:77043, anticorps DNA polymerase delta 2, accessory subunit, anticorps polymerase (DNA directed), delta 2, regulatory subunit, anticorps polymerase (DNA directed), delta 2, accessory subunit L homeolog, anticorps POLD2, anticorps Pold2, anticorps pold2.L, anticorps pold2

Sujet: In eukaryotic cells, 3 types of DNA polymerases (pol), pol alpha, pol delta and pol epsilon function in accurate and efficient DNA replication. Pol delta is a heteromultimeric enzyme composed of a 125 kDa major catalytic subunit and three smaller accessory subunits. Pol delta requires a number of accessory molecules to exert its full activity. Proliferating cell nuclear antigen (PCNA) forms a doughnut-shaped trimer with a 35 Ä hole and works as the sliding clamp and replication factor C acts as the clamp loader to improve Pol delta processivity. Pol delta is also involved in nucleotide excision repair of DNA.Synonyms: DNA polymerase delta subunit 2, DNA polymerase delta subunit p50

ID gène: 5425

NCBI Accession: NP_001120690

UniProt: P49005

Pathways: Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA