POLD2 anticorps (AA 419-469)

N° du produit ABIN7455022

Détail du produit anti-POLD2 anticorps

Antigène: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Épitope: AA 419-469

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLD2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-PolD2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 419 and 469

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur POLD2

Antigène: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Autre désignation: PolD2 (POLD2 Produits)

Synonymes: anticorps 50kDa, anticorps p50, anticorps po1D2, anticorps cdc1, anticorps si:dz150f13.3, anticorps zgc:55633, anticorps zgc:77043, anticorps DNA polymerase delta 2, accessory subunit, anticorps polymerase (DNA directed), delta 2, regulatory subunit, anticorps polymerase (DNA directed), delta 2, accessory subunit L homeolog, anticorps POLD2, anticorps Pold2, anticorps pold2.L, anticorps pold2

Sujet: Background: DNA polymerase delta subunit 2 (PolD2) is the 50- kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. PolD2 is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA [taken from NCBI Entrez Gene (Gene ID: 5425)].

ID gène: 5425

NCBI Accession: NP_001120690

UniProt: P49005

Pathways: Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA