LILRB2 anticorps (AA 51-184)

N° du produit ABIN5684070

Détail du produit anti-LILRB2 anticorps

Antigène: LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))

Épitope: AA 51-184

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LILRB2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)

Purification: purified

Immunogène: Purified recombinant fragment of human LILRB2 (AA: 51-184) expressed in E. coli.

Clone: 2G7E11

Isotype: IgG2a

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur LILRB2

Antigène: LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))

Autre désignation: LILRB2 (LILRB2 Produits)

Synonymes: anticorps CD85D, anticorps ILT-4, anticorps ILT4, anticorps LIR-2, anticorps LIR2, anticorps MIR-10, anticorps MIR10, anticorps leukocyte immunoglobulin-like receptor subfamily A member 3, anticorps leukocyte immunoglobulin like receptor B2, anticorps LOC100433990, anticorps LILRB2

Sujet:

Description: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Aliases: ILT4, LIR2, CD85D, ILT-4, LIR-2, MIR10, MIR-10

Poids moléculaire: 65 kDa

ID gène: 10288

HGNC: 8771

Pathways: Cellular Response to Molecule of Bacterial Origin