LILRB2 anticorps (AA 479-598)

N° du produit ABIN6143218

Détail du produit anti-LILRB2 anticorps

Antigène: LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))

Épitope: AA 479-598

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LILRB2 est non-conjugé

Application: Western Blotting (WB)

Séquence: LFLILRHRRQ GKHWTSTQRK ADFQHPAGAV GPEPTDRGLQ WRSSPAADAQ EENLYAAVKD TQPEDGVEMD TRAAASEAPQ DVTYAQLHSL TLRRKATEPP PSQEREPPAE PSIYATLAIH

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 479-598 of human LILRB2 (NP_005865.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LILRB2

Antigène: LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))

Autre désignation: LILRB2 (LILRB2 Produits)

Synonymes: anticorps CD85D, anticorps ILT-4, anticorps ILT4, anticorps LIR-2, anticorps LIR2, anticorps MIR-10, anticorps MIR10, anticorps leukocyte immunoglobulin-like receptor subfamily A member 3, anticorps leukocyte immunoglobulin like receptor B2, anticorps LOC100433990, anticorps LILRB2

Sujet: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.,LILRB2,CD85D,ILT-4,ILT4,LIR-2,LIR2,MIR-10,MIR10,Immunology & Inflammation,CD markers,LILRB2

Poids moléculaire: 51 kDa/55 kDa/64 kDa/65 kDa

ID gène: 10288

UniProt: Q8N423

Pathways: Cellular Response to Molecule of Bacterial Origin