LILRB2 anticorps (AA 1-100)

N° du produit ABIN1713554

Détail du produit anti-LILRB2 anticorps

Antigène: LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))

Épitope: AA 1-100

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LILRB2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human LILRB2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur LILRB2

Antigène: LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))

Autre désignation: LILRB2 (LILRB2 Produits)

Synonymes: anticorps CD85D, anticorps ILT-4, anticorps ILT4, anticorps LIR-2, anticorps LIR2, anticorps MIR-10, anticorps MIR10, anticorps leukocyte immunoglobulin-like receptor subfamily A member 3, anticorps leukocyte immunoglobulin like receptor B2, anticorps LOC100433990, anticorps LILRB2

Sujet:

Synonyms: CD85D, CD85 antigen-like family member D, CD85d, CD85d antigen, ILT 4, ILT-4, ILT4, Immunoglobulin like transcript 4, Immunoglobulin-like transcript 4, Leukocyte immunoglobulin like receptor 2, Leukocyte immunoglobulin like receptor subfamily B member 2, Leukocyte immunoglobulin-like receptor 2, Leukocyte immunoglobulin-like receptor subfamily B member 2, Leukocyte immunoglobulin-like receptor, subfamily B with TM and ITIM domains, member 2, LILRA6, LILRB2, LIR 2, LIR-2, LIR2, LIRb, LIRB2_HUMAN, MIR 10, MIR-10, MIR10, Monocyte/macrophage immunoglobulin like receptor 10, Monocyte/macrophage immunoglobulin-like receptor 10.

Background: Leukocyte immunoglobulin-like receptors (LIRs) are members of the immunoglobulin superfamily of glycoproteins and are predominantly expressed by monocytes, B cells, dendritic cells, natural killer (NK) cells, peripheral blood leukocytes and tissues such as placenta, lung and liver. These receptors all contain a cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM), have an inhibitory function and are type I membrane proteins. When they bind to MHC (or other ligands) and ITIM is tyrosine phosphorylated, protein-tyrosine phosphatases are recruited and an inhibitory signal cascade triggered. ILT-4, also designated LIR-2, MIR-10 or CD85D antigen, competes with CD8A for binding to class I MHC antigens.

ID gène: 10288

UniProt: Q8N423

Pathways: Cellular Response to Molecule of Bacterial Origin