ARHGDIA anticorps (Internal Region)

N° du produit ABIN568700

L’anticorps anti-ARHGDIA Polyclonal Chèvre est utilisé pour la détection de ARHGDIA dans des échantillons de Humain, Souris, Rat, Chien et Boeuf (Vache). Il a été validé pour WB et EIA.

Aperçu rapide pour ARHGDIA anticorps (Internal Region) (ABIN568700)

Antigène: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGDIA est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-ARHGDIA anticorps

Épitope: Internal Region

Séquence: C-QLAQIAAENE

Specificité: Recognizes ARHGDIA.

Réactivité croisée (Details): Species reactivity (expected):Human, Dog, Cow.
Species reactivity (tested):Mouse, Rat.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequencefrom the internal region of the protein sequence according to NP_004300.1. Genename: ARHGDIA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ARHGDIA

Antigène: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Autre désignation: ARHGDIA / GDIA1

Sujet: Rho GDP-dissociation inhibitor 1, also known ARHGDIA, belong to the RAS gene superfamily encoding small guanine nucleotide exchange (GTP/GDP) factors. Localized to the cytoplasm, ARHGDIA inhibits the dissociation of GDP from Rho proteins, thereby preventing GTP from binding to and subsequently activating Rho proteins. In humans ARHGDIA can be phosphorylated at Ser 101 by p21-activated kinase, an event that inhibits ARHGDIA activity and may result in positive feedback regulation of certain ARHGDIA target proteins.Synonyms: Rho GDI 1, Rho GDP-dissociation inhibitor 1, Rho-GDI alpha, RhoGDI1

ID gène: 396

NCBI Accession: NP_004300

UniProt: P52565

Pathways: Neurotrophin Signaling Pathway