MAP2K5 anticorps (pSer311, pThr315)

N° du produit ABIN5688896

Cet anticorps anti-MAP2K5 Polyclonal Lapin (ABIN5688896) détecte spécifiquement MAP2K5 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Poulet, Xenopus laevis et Poisson zèbre (Danio rerio).

Aperçu rapide pour MAP2K5 anticorps (pSer311, pThr315) (ABIN5688896)

Antigène: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Poulet, Xenopus laevis, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP2K5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAP2K5 anticorps

Épitope: pSer311, pThr315

Purification: Affinity Purified

Immunogène: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser311, Thr315 of MEK5.

Information d'application

Indications d'application: The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with mouse, human, chicken, bovine, canine, non-human primate, Xenopus, and Zebrafish tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Stock: -20 °C

Stockage commentaire: MEK5 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Détails sur MAP2K5

Antigène: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Autre désignation: MEK5

Sujet: MEK5 (also known as MKK5) is a dual specificity serine/threonine protein kinase belonging to the MAP kinase kinase family. MEK5 has been shown to specifically activate ERK5 (Zhou et al., 1995) whereas MEK5 itself is regulated by MEKK3 (Chao et al., 1999). An important link between MEK5 and metastatic prostrate cancer has been demonstrated (Mehta et.al., 2003). Dual phosphorylation of Ser311 and Thr315 have been implicated in cell proliferation (Cameron et al., 2004).

Poids moléculaire: 49 kDa

ID gène: 29568

UniProt: Q62862

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway