IL-11 anticorps (Biotin)

N° du produit ABIN5689027

L’anticorps anti-IL-11 Polyclonal Lapin est utilisé pour la détection de IL-11 dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour IL-11 anticorps (Biotin) (ABIN5689027)

Antigène: IL-11 (IL11) (Interleukin 11 (IL11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-11 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA

Détail du produit anti-IL-11 anticorps (Biotin)

Purification: Anti-hIL-11 specific antibody was purified by affinity chromatography and then biotinylated.

Immunogène: Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hIL-11 (human IL-11).

Information d'application

Indications d'application: ELISA:

To detect hIL-11 by direct ELISA (using 100 μ,L/well antibody solution) this antibody can be used at a concentration of 0.15 - 0.30 μ,g/mL. Used in conjunction with compatible secondary reagents, allows the detection of at least 0.2 ng/well of recombinant hIL-11.

Sandwich

To detect hIL-11 by sandwich ELISA (using 100 μ,L/well antibody solution) a concentration of 0.25 - 1.0 μ,g/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with our Polyclonal Anti-Human IL-11 (XP-5164) as a capture antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hIL-11.

Western Blot:

To detect hIL-11 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 μ,g/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hIL-11 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Stock: -20 °C

Stockage commentaire: IL-11 antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. Avoid repeated freeze-thaw cycles.

Détails sur IL-11

Antigène: IL-11 (IL11) (Interleukin 11 (IL11))

Autre désignation: IL-11

Sujet: Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production. Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.

ID gène: 3589

UniProt: P20809

Pathways: Signalistation JAK/STAT, Negative Regulation of Hormone Secretion