MAP2K5 anticorps (AA 311-315)

N° du produit ABIN5689204

L’anticorps anti-MAP2K5 Polyclonal Lapin est utilisé pour la détection de MAP2K5 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour MAP2K5 anticorps (AA 311-315) (ABIN5689204)

Antigène: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP2K5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAP2K5 anticorps

Épitope: AA 311-315

Specificité: This antibody detects endogenous level of total MEK5 protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide

Immunogène: MEK5 antibody was raised against a peptide sequence around aa. 311-315 (K-T-Y-V-G ) derived from Rat MEK5.

Information d'application

Indications d'application: Western Blot: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur MAP2K5

Antigène: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Autre désignation: MEK5

Sujet: A family of protein kinases located upstream of the MAP kinases andresponsible for their activation has been identified. The prototype member ofthis family, designated MAP kinase kinase, or MEK-1, specifically phospho-rylates the MAP kinase regulatory threonine and tyrosine residues present inthe Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resem-bles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to acti-vate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activatesboth p38 and JNK MAP kinases. MEK-5 appears to specifically phosphory-late ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7)phosphorylates and activates the JNK signal transduction pathway.

Poids moléculaire: 49 kDa

ID gène: 29568

NCBI Accession: NP_001029159

UniProt: Q62862

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway