SAPK, JNK (AA 181-185) anticorps
Aperçu rapide pour SAPK, JNK (AA 181-185) anticorps (ABIN5689246)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 181-185
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Specificité
- This antibody detects endogenous level of total SAPK/JNK protein.
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Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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Immunogène
- SAPK/JNK (Ab-183) antibody was raised against a peptide sequence around aa.181~185 (M-M-T-P-Y) derived from Human SAPK/JNK.
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Indications d'application
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store antibody at -20°C for up to one year.
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- SAPK, JNK
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Autre désignation
- SAPK / JNK
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Sujet
- Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.
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Poids moléculaire
- 46, 54 kDa
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ID gène
- 5601
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NCBI Accession
- NP_001128516
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UniProt
- P45984, P53779
Antigène
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