SAPK, JNK (AA 181-185) anticorps
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- Antigène
- SAPK, JNK
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Épitope
- AA 181-185
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Inconjugué
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Application
- Immunohistochemistry (IHC), Western Blotting (WB)
- Specificité
- This antibody detects endogenous level of total SAPK/JNK protein.
- Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Immunogène
- SAPK/JNK (Ab-183) antibody was raised against a peptide sequence around aa.181~185 (M-M-T-P-Y) derived from Human SAPK/JNK.
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- Indications d'application
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store antibody at -20°C for up to one year.
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- Antigène
- SAPK, JNK
- Autre désignation
- SAPK / JNK
- Synonymes
- anticorps JNK-55, anticorps JNK2, anticorps JNK2A, anticorps JNK2ALPHA, anticorps JNK2B, anticorps JNK2BETA, anticorps PRKM9, anticorps SAPK, anticorps SAPK1a, anticorps p54a, anticorps p54aSAPK, anticorps AI851083, anticorps Prkm9, anticorps mitogen-activated protein kinase 9, anticorps MAPK9, anticorps Mapk9
- Sujet
- Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.
- Poids moléculaire
- 46, 54 kDa
- ID gène
- 5601
- NCBI Accession
- NP_001128516
- UniProt
- P45984, P53779
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