ITGA4 anticorps (AA 1024-1028)

N° du produit ABIN5689252

L’anticorps anti-ITGA4 Polyclonal Lapin est utilisé pour la détection de ITGA4 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour ITGA4 anticorps (AA 1024-1028) (ABIN5689252)

Antigène: ITGA4 (Integrin alpha 4 (ITGA4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGA4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ITGA4 anticorps

Épitope: AA 1024-1028

Specificité: This antibody detects endogenous level of total LPAM-1(Integrin α,4, CD49d) protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: LPAM-1 (Integrin a4, CD49d) antibody was raised against a peptide sequence around aa.1024~1028 (Y-I-N-S-K) derived from Human LPAM-1 (Integrin α,4, CD49d).

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur ITGA4

Antigène: ITGA4 (Integrin alpha 4 (ITGA4))

Autre désignation: LPAM 1

Sujet: Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.

Poids moléculaire: 70, 140, 180 kDa

ID gène: 3676

NCBI Accession: NP_000876

UniProt: P13612

Pathways: Integrin Complex