E2F1 anticorps (AA 430-434)

N° du produit ABIN5689264

L’anticorps Lapin Polyclonal anti-E2F1 a été validé pour WB. Il convient pour détecter E2F1 dans des échantillons de Humain et Souris.

Aperçu rapide pour E2F1 anticorps (AA 430-434) (ABIN5689264)

Antigène: E2F1 (E2F Transcription Factor 1 (E2F1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp E2F1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-E2F1 anticorps

Épitope: AA 430-434

Specificité: This antibody detects endogenous levels of total E2F-1 protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: E2F-1 antibody  was raised against a peptide sequence around aa.430~434 (G-D-L-T-P) derived from Human E2F-1.

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur E2F1

Antigène: E2F1 (E2F Transcription Factor 1 (E2F1))

Autre désignation: E2F 1 

Sujet: Transcription activator that binds DNA cooperatively with dp proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-1 binds preferentially RB1 protein, in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent apoptosis.

Poids moléculaire: 70 kDa

ID gène: 1869

NCBI Accession: NP_005216

UniProt: Q01094

Pathways: Signalisation p53, Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy